The sclera, also known as the white of the eye, is the opaque, fibrous, protective, outer layer of the eye containing mainly collagen and some elastic fiber.[2] In humans, the whole sclera is white, contrasting with the coloured iris, but in other mammals the visible part of the sclera matches the colour of the iris, so the white part does not normally show. In the development of the embryo, the sclera is derived from the neural crest.[3] In children, it is thinner and shows some of the underlying pigment, appearing slightly blue. In the elderly, fatty deposits on the sclera can make it appear slightly yellow.
The human eye is relatively rare for having an iris that is small enough for its position to be plainly visible against the sclera. This makes it easier for one individual to infer where another individual is looking, and the cooperative eye hypothesis suggests this has evolved as a method of nonverbal communication.